James Papatzimas
![James Papatzimas James Papatzimas](https://proteindegradation.com/wp-content/uploads/sites/82/2024/06/James-Papatzimas-150x150.png)
Company: Novartis
Job title: Principal Scientist
Seminars:
Gluing the Pieces Together, to Break it All Down: Harnessing Novel E3 Ligases for Molecular Glue Degraders 12:00 pm
The TPD field currently lacks rational chemical design principles for converting protein-targeting ligands into molecular glues Using known protein binders, we sought to identify transposable motifs which would convert these ligands into protein degraders RNF126, a previously unliganded RING E3 ligase, was determined to be an amenable ligase mediating a multitude of neo-substrate recognition events,…Read more
day: Bootcamp Day