What’s New for 2023?
Always striving to remain at the cutting edge of TPD development, at this year’s summit we’re placing more onus on covalency in degrader discovery and development, guided by the insights from leaders like Dan Nomura and Eric Fischer.
Whilst continuing to deliver breaking clinical updates first and foremost from the field’s key players; Nurix Therapeutics, C4 Therapeutics, Foghorn Therapeutics, Arvinas, and Kymera Therapeutics, this year we have added an additional discovery track, to cater for and support the rapidly expanding network of early-stage developers in the field.
Key Agenda Highlights
Brand New Day:
TPD in CNS: A New Frontier Medicine
CNS drug discovery and development is experiencing a renaissance with the advent of targeted protein degradation. Degrader molecules have the potential to remove disease-causing proteins like parkin and amyloids. Join CNS pioneers like Arvinas, Origami Therapeutics, NysnoBio, Amphista, and Prazer Therapeutics as they unite for the very first time under one roof to tackle oral bioavailability, biomarker discovery, brain penetration and more.
Brand New Tracks:
From Target Validation to Lead Optimization
With overwhelming demand for additional discovery presentations at the 5th TPD Summit, we have introduced…
‘Target ID & Hit Validation Track’:
Expect to engage in open discussion around novel E3 ligase identification, validation, and characterization, as well as discovery efforts into ligands and binders for this high value protein class.
‘Lead Optimization Track’:
Get granular with expert medicinal chemistry insight into candidate degrader biochemical properties to create highly potent, orally bioavailable, tissue selective compounds.
Brand New Voices:
The Key Opinion Leaders are Back
At a time when this community is poised for more clinical success yet continues to battle for available funding to progress this pioneering drug modality, uniting the industry’s key thought leaders is crucial. Hear what Dan Nomura, Matt Disney, and Gwenn Hansen have to say about the future of TPD and come armed with the questions that will accelerate your internal decision-making and make your entry into clinic smoother and faster.
2nd TPD Awards!