Abhishek Dogra

Company: A-Alpha Bio

Job title: Director - Medicinal Chemistry & Induced Proximity

Seminars:

Discovering & Characterizing Latent E3 Ligase Protein-Protein Interactions Against 150 Therapeutic Targets 9:00 am

Over 100 protein-protein interactions were identified between therapeutically relevant targets and a diverse set of ligases A subset of these interactions was further characterized using site-directed mutagenesis to define the interface and explore the ability to modulate the interaction These protein-protein interactions were used to prioritize small molecule discovery campaigns aimed at identifying molecular gluesRead more

day: Focus Day