Mark Niosi

Company: Pfizer

Job title: Scientist

Seminars:

Optimizing in vitro ADME assays to Deliver Orally Bioavailable PROTACs & Innovation for Degrader Safety Assessments 11:30 am

A significant challenge with oral bioavailability for large and complex molecules like PROTACs, lies in their propensity to experience poor intestinal absorption. Factors such as low membrane permeability, instability within the intestinal environment, and susceptibility to enzymatic degradation, all can hinder their ability to be orally bioavailable. Attend this workshop to: • How useful are…Read more

day: Workshop Day