Eugene Chekler

Company: Bristol Myers Squibb

Job title: Director

Seminars:

Predicting & Optimizing the Selectivity Profiles of Novel CELMoD Compounds 10:00 am

Unlike achieving potency and selectivity for traditional small molecule inhibitors, reducing degradation of neosubstrate off-targets is complicated by the ternary nature of the complex formed between the POI, CRBN, and the CELMoD agent Herein we disclose an analysis of our glutarimide CELMoD library using a simple algorithm to identify the interpretable chemical features correlated with…Read more

day: Focus Day