Roundtable Discussion: Expanding E3 ligase Platforms for Targeted Protein Degradation
Time: 1:30 pm
day: Bootcamp Day
Details:
- Current state of the art, selection of Next-Gen E3 ligases and winning screening strategies, e.g. Rational design Hit ID, phenotypic function 1st, computational AI-ML
- Accelerated workflows for binder to degrader conversion
- Tissue- specific and tissue restricted TPD : has this underdelivered and what are the main obstacles?
- Expanding molecular glue potential of E3 ligands
