New Approach for TPD: Targeting the Secretory Translocon (Sec61) to Selectively Eliminate Extracellular Proteins
Time: 3:00 pm
day: Post-Conference Focus Day
Details:
- Mother Nature pioneered targeting of Sec61 for secretory protein degradation
- Selectivity is enabled by virtue of the unique sequences of Signal Peptides across the secretome
- Synthetic small molecules are capable of selectively eliminating secreted and membrane proteins
