Molecular Glues & Bifunctional Compounds: Therapeutic Modalities Based on Induced Proximity
Time: 9:00 am
day: Research Day
Details:
- Exploiting similarity of molecular glues and bifunctional compounds to hot spots, missense mutations, and posttranslational modifications (PTMs)
- Coming full circle from natural product glues to simple synthetic compounds back to natural product-like glue compounds with high structural diversity
- Methods to discover cooperative molecular glues and bifunctionals for biomedical targets of interest