Discovery of Novel E3 Ligase Binders via Rapid Screening of DNA-Encoded Libraries
Time: 12:00 pm
day: Focus Day
Details:
- DNA-encoded library technology enabled the identification of novel binders for buckets of E3 ligases in a cost-efficient way
- Examples of potent binders for both ubiquitous E3 and tissue specific E3 Ligases directly from DEL
- Refined workflow towards ligase binder and PROTAc discovery at GSK
