Discovery of Novel E3 Ligands for Targeted Protein Degradation
Time: 3:30 pm
day: Focus Day
Details:
- Uncovering the catalytic mechanism to achieve higher efficacy, the ability to target previously undruggable proteins and the potential to deliver drug activity to selective tissues in TPD
- Demonstrating how E3 ligands hold the key to realize the full potential of TPD but are currently limited
- Discussing our rationale and efforts in discovering novel E3 ligands for targeted protein degradation