Degradation of Key Intracellular Targets via the Cytosolic Delivery of Recombinant BioPROTACS
Time: 10:00 am
day: Post-Conference Focus Day
Details:
- Modification of antibodies and proteins with anionic polypeptides allows for complexation with cationic lipids and efficient intracellular delivery
- Recombinant BioPROTACS can be used to efficiently degrade “undruggable” intracellular targets
- Delivery of recombinant BioPROTACS may lead to significantly fewer differentially-regulated “off-target” proteins compared with mRNA encoded BioPROTACS
