Stephanie Leuenroth-Quinn

Company: US Food & Drug Adminstration

Job title: Pharmacologist

Seminars:

Panel Discussion: Developing TPD Study Design for Preclinical Safety Assessment of Degraders 8:15 am

• Are current guidelines for assessing the safety of small-molecule therapeutics adequate – are there TPD specific risks? • What is the current decision-making framework for assessing TPD safety risks, e.g. how to assess off-target degradation risks in vitro, and how to select preclinical safety species? • Should safety assessment of PROTACs and Molecular Glues…Read more

day: Day 1