Andreas Weiss
Senior Vice President, Protein Homeostasis Evotec
Seminars
Tuesday 27th October 2026
Expanding the Molecular Glue Landscape to Enable Program Generation Across Multiple Therapeutic Areas
11:45 am
- Introducing complementary discovery approaches combining proteome-wide neo-substrate identification and transcriptomics-driven phenotypic screening for molecular glue discovery beyond CRBN
- Showcasing how focused and high-diversity chemical libraries reveal novel degrader mechanisms and therapeutic targets across multiple disease areas
- Demonstrating a scalable path from unbiased hit discovery to validated molecular glue programs enabled by a novel E3 ligase platform and advanced cellular profiling
