The In Vitro ADME Playbook for Protein Degraders: What’s Different?

1:30 pm - Tuesday 27th October 2026

  • Presenting workflow adaptations for in vitro ADME challenges of heterobifunctional protein degraders
  • Case study: In vitro characterization of ARV-825 and JNJ-1013, including metabolism, metabolite identification, DDI assessment, and in vitro immunogenicity
  • Considerations for generating actionable ADME and safety data to support protein degrader discovery and development

Speakers:

Scientific Advisor, ADMET
BioIVT