Tina Mueller
Scientific Advisor, ADMET BioIVT
Seminars
Tuesday 27th October 2026
The In Vitro ADME Playbook for Protein Degraders: What’s Different?
1:30 pm
- Presenting workflow adaptations for in vitro ADME challenges of heterobifunctional protein degraders
- Case study: In vitro characterization of ARV-825 and JNJ-1013, including metabolism, metabolite identification, DDI assessment, and in vitro immunogenicity
- Considerations for generating actionable ADME and safety data to support protein degrader discovery and development
