Randolph Lopez
Co-Founder & Chief Technology Officer A-Alpha Bio Inc.
Randolph co-founded A-Alpha Bio after receiving his PhD in Bioengineering from the University of Washington. Before graduate school, Randolph was a Process Development Engineer at Illumina, where he was responsible for improving quality control efficiency and translating products into manufacturing. During graduate school, Randolph expanded his technical breadth into synthetic biology and computer science, providing a well-rounded foundation for the development and implementation of AlphaSeq + AlphaBind. Outside of work, Randolph enjoys traveling around the world, running long distances, and eating ramen.
Seminars
When starting molecular glue development from scratch, finding the right interaction to stabilize is the most crucial
step. In this workshop, you will learn to decode targetligase pairs and accurately visualize ternary complexes to accelerate molecular glue discovery. We will cover:
- How to identify the right target-ligase pairings with high-throughput assays
- Choosing the best libraries, assays, and biophysical methods to discover and validate hits for molecular glue development
- Using in silico modeling to optimize ternary complex visualization
