Peter Ung
Principal Scientist Genentech
Seminars
Thursday 29th October 2026
Optimizing the Next Generation Degraders with Better Informatics, Descriptors & Predictive Modeling
9:30 am
- Development of internal tools to manage, visualize, and streamline the analysis of PROTAC and molecular glue molecules
- Evaluating the predictiveness of 2D/3D descriptors for PROTAC/Glue
- Development of ML model of EPSA to facilitate design of permeable PROTACs
Thursday 29th October 2026
Discussion: Harnessing AI & Computational Modelling to Optimize Design, Specificity & Efficacy of Induced Proximity Molecules to Support the Development of Tolerable, Selective Therapies
10:00 am
- Optimizing PROTAC linkers & E3 ligase pairing with AI and machine learning tools for enhanced selectivity and potency
- Transforming molecular glue design with AI to predict target engagement, enhance selectivity and minimize off-target degradation
- Employing computational tools and modelling approaches to inform therapeutic strategy across induced proximity modalities
