Mat Sowa
Vice President, Lead Discovery C4 Therapeutics Inc
Seminars
Thursday 29th October 2026
Molecular Glue DEL Screening to Produce Expansive Datasets for Systematic Hit Identification for High Value Therapeutic Targets
11:45 am
- Development and implementation of a molecular glue DEL screening platform at scale
- Leveraging PPI for targets with high unmet medical need that have proven limited or intractable for ligand finding efforts
- A combination of approaches increases confidence in hit calling for off-DNA synthesis of hits and leads to improved validation