Hongbo Zhang
Chief Scientific Officer & Head of Drug Discovery Service HitChem
Seminars
Wednesday 28th October 2026
From Design to Application: A CRBN Molecular Glue Library Derived from In-House & Literature-Validated CRBN Binders
3:15 pm
- A systematic exploration of the chemical space of CRBN-binding scaffolds (300 compounds synthesized and tested) , SAR insights and highlighting representative, structurally novel, and effective binders
- An overview of HitChem’s CRBN molecular glue (MG) library design strategy, along with HTS case studies across multiple targets
