Henrik Daub
Chief Scientific Officer NEOsphere Biotechnologies GmbH
Seminars
Tuesday 27th October 2026
A Proteome-Wide Screening Engine Delivering Partner-Ready Molecular Glue Degraders at Scale
12:00 pm
- Large-scale proteomic library screening has identified molecular glue degraders against 300+ targets — including CDK4 — across indications from I&I to oncology, ready to license and fuel partner programs
- Linking chemical structures of entire libraries to proteome-wide degradation and interactome profiles supports selectivity optimization and SAR
- Proteomics-driven AI/ML enables rational molecular glue prediction and design — shortening discovery timelines and increasing hit-to-lead success rates
