Debora Bonenfant
Vice President & Head of Proteomics Monte Rosa Therapeutics
Seminars
Thursday 29th October 2026
Scaling Proteomics for High-Throughput CRBN Target Discovery
1:45 pm
- Scalable proteomics platform transitioning from TMT-based discovery to DIA-enabled high-throughput profiling
- Establishment of a platform to map the CRBN target space, extending neosubstrate recognition beyond the canonical β‑hairpin G‑loop degron
- Discovery of a molecular glue degrader MRT-31619, that drives homo-dimerization of CRBN and promotes its fast, potent, and selective degradation
Thursday 29th October 2026
Chair’s Opening Remarks
8:20 am
Thursday 29th October 2026
Chair’s Closing Remarks
2:45 pm
