Catherine Henry
Seminars
Monday 27th October 2025
Developing a Screening Funnel for Targeted Protein Degraders
11:30 am
- Establishing high-throughput assays for on and off-target degradation
- Applying learnings from drug discovery efforts in the “beyond rule of 5” chemical space to predict and assess oral bioavailability
- Profiling PK/PD in vivo and conducting lead optimization studies (Tier 2 ADME, selectivity, and cross-species DMPK)
