Antony Sheehan
Director Of Immunoassays Site Head TGR BioSciences
Seminars
Wednesday 28th October 2026
Detecting Endogenous Protein Interactions & RIPTACs with No-Wash Assays: The New Frontier for AlphaLISA™ SureFire® Technology
12:00 pm
- Understand the role of endogenous PPIs and ternary complexes in drug discovery and how AlphaLISA™ SureFire® assay technology is ideally suited to their detection in native cell systems
- Explore AR/BRD4 and ER/BRD4 RIPTAC ternary complexes in multiple prostate and breast cancer cell models
- Examine myddosome complex assembly data in relevant wild-type cell models and their perturbance with PROTAC degraders
- How the open, modular & flexible platform design of AlphaLISA™ SureFire® technology can be customised to measure a wide range of RIPTAC Target/Effector Protein Ternary Complexes in native cell models
