Transforming Molecular Glue Discovery with ToRNeDO: An Empirical, Cell-Based Discovery Platform
- Presenting ToRNeDO, SyntheX’s molecular glue selection platform that bypasses serendipitous screening
- Enabling functional selection of target/ligase pairs and mapping of novel degrons for rational glue design
- Discovering a molecular glue against a novel effector with exquisite target selectivity to drive new therapeutic strategies