Optimizing Drug Discovery with the Development of an Ultra High-Throughput, Lysate-Compatible Induced Proximity Screening System
- Advantages of cell lysate-based screening over recombinant protein screens
- Adapting high-throughput combinatorial chemistry to improve upon their sensitivity, enable their compatibility with cell lysates, and allow their discovery of induced proximity small molecules
- Sharing proof-of-concept data (either full scale, or if not yet available, model system) for Birdwood’s platform