Discovery of Molecular Glues at Scale
- ApoXY is a massively multiplexed platform to discover molecular glues. It enables high throughput screening of molecules against dozens of protein pairs simultaneously inside of eukaryotic cells
- ApoXY robustly detects weakly induced interactions that may be degrading or non-degrading, enabling discovery of molecular glues agnostic of therapeutic mechanism of action
- We are applying ApoXY to discover best-in-class and first-in-class molecular glues in oncology and immunology