Rick Ewing
![Rick Ewing Rick Ewing](https://proteindegradation.com/wp-content/uploads/sites/82/2024/06/Rick-Ewing-150x150.jpg)
Company: Rapafusyn
Job title: Vice President, Head of Chemistry
Seminars:
Non-Degrading Molecular Glues: A Platform for Finding Novel Chemical Matter for Inhibiting Intracellular & Transmembrane Proteins 2:00 pm
The described macrocycles form ternary complexes comprising a presenter protein (FKBP12), the molecular glue, and a target protein. Inhibition through formation of a ternary complex often results in potency, selectivity over homologous proteins and favorable drug like properties such as slow binding kinetics The construction of DEL and array libraries of molecular glues will be…Read more
day: Post-Conference Focus Day