Pre-Conference Bootcamp Day
Tuesday, October 25
Want to understand the basic principles and familiarize yourself with key terms and technologies?
Look no further than the TPD 101 Bootcamp Day at the Targeted Protein Degradation Summit where you will learn the important foundations of the field preparing you and increasing your confidence in the discussions that lie in the deeper-dive days ahead!
8:00 am Registration & Coffee Morning
8:25 am Chair’s Opening Remarks
8:30 am Diversity, Equality & Inclusion Panel Discussion
Synopsis
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9:15 am An Introduction to Targeted Protein Degradation
Synopsis
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9:45 am High-Throughput Assay Technologies for Accelerating the Discovery & Enhancement of Targeted Protein Degradation Therapeutics
Synopsis
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10:15 am Degraders Versus Inhibitors: A Tale of Two Drug Discovery Modalities
Synopsis
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10:45 am Targeted Degradation as a Means to Address Resistance Common to Kinase Targeted Therapies
Synopsis
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11:15 am Morning Break & Refreshments
12:15 pm Deep-Dive into the Mechanistic Understanding of Ubiquitination
Synopsis
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12:45 pm Understanding the Ternary Complex Formation
Synopsis
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1:15 pm Informatics Accelerated CRBN Glue Lead Discovery
Synopsis
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1:45 pm Expression & Characterization of Novel Tissue Selective E3 Ligases
Synopsis
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2:15 pm Networking Lunch
3:15 pm Round Table Discussions | Dissecting the Drug Development Pipeline
Discovery - Understanding early discovery considerations,
understanding terminology
Kevin Woller, Principal Research Scientist, Abbvie
Pre-Clinical - How to take your candidate
forward into animal studies and
understanding what species are best
Jacqueline Kinyamu-Akunda, Senior Scientific Director, Nonclinical Safety, Janssen R&D
Clinical - Where is the field currently
and how to approach emerging
challenges such as resistance